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Scientists identify novel target for heart failure therapy

Scientists identify novel target for heart failure therapyWashington, Mar 17: Researchers from Thomas Jefferson University have identified a novel signalling pathway that can be a potential target for heart failure therapy.

The pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction.

Aldosterone production is mediated by a protein called beta-arrestin-1. Aldosterone is secreted by the adrenal cortex and its levels are elevated in chronic heart failure.

''Transformers 3'' to release on July 1, 2011

''Transformers 3'' to release on July 1, 2011Washington, March 17 : Paramount and DreamWorks have decided on July 1, 2011 to be the release date for `Transformers 3'.

Paramount insiders have revealed that studio bosses made this move because they wanted to claim the date before any competitor did, considering that the 2011 summer release calendar is filling up.

The release date for the film has been selected despite the fact that no deals have been inked with director Michael Bay or franchise stars Shia LaBeouf and Megan Fox.

Guitarists’ brains become synchronised during gigs just like their guitars

Guitarists’ brains become synchronised during gigs just like their guitarsWashington, March 17: When a group of musicians perform during a concert, their brains become synchronised in the same fashion as their instruments do, according to a new study.

Researchers from the Max Planck Institute for Human Development in Berlin and the University of Salzburg came to this conclusion after recording the brain electrical activity in eight pairs of guitarists with the aid of electroencephalography (EEG).

Discovery on way to ISS with eye on space junk

Discovery on way to ISS with eye on space junkWashington - The space shuttle Discovery was on its way to the International Space Station on Monday as ground crews monitored a piece of space junk that could prompt a change of course.

A piece of an old satellite could require the ISS to perform an avoidance manoeuvre, forcing Discovery to slightly change course in order to arrive at the ISS on Tuesday.

Obama angry over AIG's huge bonuses, vows to block them

Obama angry over AIG's huge bonuses, vows to block themWashington  - US president Barack Obama Monday added his anger to mounting criticism of the bailed-out insurance giant American International Group Inc (AIG) over its payment of huge bonuses and vowed to block them.

The firm has revealed it intends to hand out 1 billion dollars in reward pay, including 165 million dollars already given to the very traders who sold financial instruments that helped trigger the global credit crisis.

Obama unveils measures for small businesses at "heart" of economy

Obama unveils measures for small businesses at "heart" of economy Washington  - US President Barack Obama laid out a new effort Monday to help small businesses struck hard by a Wall Street crisis that has cut off their access to loans.

The administration's new plan is designed to jump-start lending by directly investing in frozen credit markets, boosting loan guarantees and forcing the 21 banks that have accepted emergency government funds to report monthly on their loans to US companies.

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