Ocular Therapeutix Inc’s Drug OTX-DP fails in Second Phase-III Clinical Trial

Ocular Therapeutix announced that its leading eye drug failed to meet one of the main goals in a second late-stage study.

The leading developer of ophthalmic therapies said that its drug, OTX-DP, is a hydrogel formulation which is effective in reducing pain in patients who had cataract surgery. But the drug failed to reduce the inflammation in the eyes, the company said.

The investigators in the first Phase III noted that while the drug performed better than a dummy version in reducing pain, it failed to distinguish itself from the placebo.

The company affirmed that the drug has to meet both the endpoints for the trail to be considered successful.

It further said it is now looking forward to meet the US Food and Drug Administration to discuss the trial results.

Middle-Aged People need to stay physically fit to lower Cardiac Arrest Risk

Chances of suffering from sudden cardiac arrest while middle-aged adults do sports activities are less. Therefore, American researchers said that these people can exercise without worrying about it.

The finding is based on a review of 1,247 sudden cardiac arrest cases involving men and women aged 35 and 65. After carrying out the review, the researchers found that 63 cases or 5% were linked with sports activities.

In the two-third cases, patients had already faced cardiovascular disease or symptoms before the sudden cardiac arrest. When all the sudden cardiac arrests were compared, sports-associated cases were most witnessed (87% versus 53%) and involved CPR (44% versus 25%) and a cardiac rhythm disturbance (84% versus 51%).

Officials test Arizona Prairie Dogs Positive for Plague

Fleas collected in northeast of Flagstaff, Arizona in Picture Canyon have been tested positive for plague. County Public Health Services District performed the task of conducting additional testing on prairie dogs Friday and disinfected their burrows.

Public health officials collected the fleas around the trails of the popular hiking area. The officials were directed to collect the fleas from that area after the prairie dogs were seen dying.

Officials have advised people to not go close to dead animals or handle dead animals or use insect repellant. Extra precaution should be taken by hikers and pet owners recreating in the Picture Canyon trail area, said the Coconino County Public Health Services District.

Breast Milk sold Online could be adulterated with Cow’s milk

The U. S. FDA has warned women about breast milk being sold online. The FDA said that it could lead to certain serious health and adulteration risks. And now, researchers are also supporting the warnings.

A novel study published in the journal Pediatrics has found that 10% of breast milk samples bought online were mixed with cow's milk. The researchers bought 102 bottles of breast milk online and then they assessed the samples for human DNA or bovine DNA from cows.

Kandiyohi County Poultry Farm tests positive for H5N2 Avian influenza

According to reports, bird flu has arrived in Minnesota's top turkey-producing county, which is Kandiyohi County. On Monday, state officials stated that a poultry farm of the county with more than 26,000 turkeys has tested positive for H5N2 avian influenza. The case is the first in Kandiyohi County and seventh in Minnesota, as per the reports.

The Minnesota Board of Animal Health confirmed on Monday that a Stearns County farm with about 76,000 turkeys has also tested positive for the virus. It was the third confirmed case of the avian influenza in Stearns County so far.

As per the reports, the avian influenza has also been confirmed at poultry farms in Pope, Lac qui Parle and Nobles counties. About 343,000 birds have been affected by the virus so far in Minnesota.

New brain-scanning technique could help detect CTE

According to a new study, a brain-scanning technique could help recognize people with a health condition associated with concussions in football and other sports. Deposits of abnormal protein in a pattern similar to that found at autopsy in the disease have been revealed in scans of 14 retired football players at risk for the condition, called chronic traumatic encephalopathy (CTE).

CTE leads to progressive brain degeneration in athletes and others, who have had suffered repeated concussions and other hits to the head. Memory loss, aggression, confusion, depression and progressive dementia are the symptoms of the condition.

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