Gene variant role in Parkinson’s uncovered

Gene variant role in Parkinson’s uncoveredRecently scientists have found out that the gene-controlling little bit of RNA may have a role to play in Parkinson's disease, thereby having the key to an effective remedy to the disorder.

An RNA bit has been found out to be present in the Parkinson disease, thereby expected to cause the destruction of neurons in the brains of fruit flies. It has in fact been demonstrated how a micro-RNA sequence, which controls and keeps down certain genes, has a role in destroying of brain cells in fruit flies.

The team of scientists studied a gene called LRRK2 for the research. This LRRK2 gene, in its mutant form, is well prevalent among the Jews of European descent and people from north Africa, and is infamous to contribute to the development of the Parkinson's disease, though it is not quite certain as of yet exactly how.

Fruit flies containing the mutant form of the LRRK2 gene were not only found to have a disrupted micro-RNA pathway linked to the gene, but also had an accumulation of toxic proteins that inhibited the brain's motor-coordinating neurons.