Washington, Nov 6 : People often ignore the general symptoms of pain, thinking that the ache doesn''t merit a trip to the doctor, however, a new study has outlined some signs that should never be ignored or they can prove fatal.

The November issue of Mayo Clinic Women''s HealthSource has brought to light 10 generally ignored symptoms, which should be reported to the doctor immediately to avoid any kind of complication.

They are:

London, Nov 6: A team of researchers has shown that a molecule called Cyclophilin D (CypD) interacts with amyloid beta (Aâ) peptide, the main constituent of plaques in the brains of Alzheimer''s patients, within the mitochondria.

The study involving a transgenic mouse model of Alzheimer’s disease suggests that blocking CypD and development of surrounding mitochondrial targets may be viable therapeutic strategies for the prevention and treatment of Alzheimer’s disease, reports Nature.

Washington, Nov 6 : Women who have a history of migraine headaches are at a significantly lower risk of breast cancer, a new study has found.

The findings have been reported in the November issue of Cancer Epidemiology, Biomarkers and Prevention by Christopher I. Li, M. D., Ph. D., and colleagues at Fred Hutchinson Cancer Research Center.

"We found that, overall, women who had a history of migraines had a 30 percent lower risk of breast cancer compared to women who did not have a history of such headaches," said Li, a breast-cancer epidemiologist and associate member of the Hutchinson Center''s Public Health Sciences Division.

Washington, Nov 6: In a new study, researchers have discovered the first gene, called CNTNAP2, linked with a common childhood language disorder, known as specific language impairment (SLI).

The discovery of the CNTNAP2 gene, which has recently been implicated in autism, may act as a crucial genetic link between the two disorders.

SLI is the most common language disorder, in which children develop unexplained difficulties in producing and understanding language

Washington, Nov 6 : Pregnant women who have a smoking habit are more than twice as likely to have children with a cleft palate or lip birth defect, a new study has found.

The findings were based on the measurement of cotinine level, a metabolite of nicotine, in the blood from about 500 pregnant women.

Washington, Nov 6 : Researchers at Hospital for Special Surgery have identified a new therapeutic target that can be used for the treatment of rheumatoid arthritis.

The research team found that manipulating a protein involved in two molecular pathways linked to inflammation could offer new therapies for rheumatoid arthritis.

They said that manipulating a protein called RBP-J involved in two molecular pathways the Notch and Toll-like receptor can lead to new therapies.