Health News

Breakthrough protein discovery may make for better TB therapy

Washington, November 6: American scientists have discovered proteins that point to “cross-talk” between the body’s immune system and the self-cleaning system, by which biological cells rid themselves of obsolete or toxic parts.

The finding by researchers from the U. S. Department of Energy’s (DOE) Lawrence Berkeley National Laboratory (Berkeley Lab) attain significance as it has long been though that a link between the two systems may yield new weapons in the fight against tuberculosis and other deadly infectious diseases.

Schools would have to upgrade furniture

Schools would have to upgrade furnitureAccording to a survey, schools would soon have to upgrade their furniture as the children have outgrown the furniture designed in 1960’s due to increase in height and weight. 

A research conducted by the Furniture Industry Research Association, compared the measurements of 1,500 children in 2001 with data from 1971. It was found that average height increase in children is at a rate of 1cm a decade, with most of the growth in the lower leg. 

''Junk'' DNA distinguishes humans from other species

Washington, Nov 5 : What was earlier considered to be "junk" DNA has now been found to be an important ingredient distinguishing humans from other species, say scientists at the Genome Institute of Singapore (GIS).

Over 50 percent of human DNA is designated as "junk" as it consists of copies of nearly identical sequences, the major source of which is internal viruses that have inserted themselves throughout the genome at various times during mammalian evolution.

By using the latest sequencing technologies, scientists proved that a large number of transcription factors—master proteins that control the expression of other genes—bind specific repeat elements.

Vitamin B3 ''cuts Alzheimer''s symptoms, lesions''

Alzheimer’s DiseaseWashington, Nov 5 : In a new study on mice, researchers have found that Nicotinamide, a form of Vitamin B3, in high doses may prevent lesions and symptoms associated with Alzheimer''s disease.

UC Irvine scientists are now conducting a clinical trial to determine its effect in humans.

Nicotinamide, was found to reduce the levels of a protein called phosphorylated tau that leads to the development of tangles, one of two brain lesions linked with Alzheimer''s.

The researchers found that the vitamin also strengthened scaffolding along which information travels in brain cells.

DNA ‘master regulator’ find may revolutionise diabetes, heart disease treatment

Washington, November 5 : Penn State researchers have identified thousands of positions where a molecular “master regulator” is located in DNA to control genes in fat cells.

Dr. Mitchell Lazar, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has revealed that the master molecule is called PPAR gamma, a target of anti-diabetic drugs.

The drugs bind to PPAR gamma in the nucleus of fat cells, which affects the expression of many genes, about twenty of which were previously known.

The latest study has uncovered about 5,300 additional sites that PPAR gamma targets in fat-cell DNA.

A drug that can help combat frailty in elderly

Washington, Nov 5: A daily dose of an investigational drug, known as MK-677, which stimulates growth hormone secretion in the body can boost muscle mass in older adults, report researchers at the University of Virginia Health System.

The discovery may prove safe and effective in reducing age-related frailty.

Published in the November 4, 2008 issue of Annals of Internal Medicine, the study showed that levels of growth hormone (GH) and of insulin-like growth factor I (IGF- I) in seniors who took MK-677 increased to those found in healthy young adults.

The drug restored 20 percent of muscle mass loss associated with normal aging.

Pages