Johannesburg - South Africa's Deputy President Phumzile Mlambo-Ngcuka was the first member of ousted President Thabo Mbeki's cabinet to confirm her resignation Tuesday.
Mlambo-Ngcuka's spokesman said she had handed in her resignation to Mbeki.
Her resignation comes two days after Mbeki stepped down as president just months before his second and last five-year term was due to run out.