Tokyo - Japan's benchmark Nikkei 225 Stock Average gave up early gains Thursday to end at a five-year low as concerns lingered over the global financial crisis.

The key Nikkei index fell 45.83 points, or 0.5 per cent, to close at 9,157.49.

But the broader Topix index of all first-section issues went up 6.1 points, or 0.68 per cent, to 905.11, a day after nine central banks lowered interest rates.

The Bank of Japan injected a record 4 trillion yen (39.8 billion dollars) into the money markets Thursday amid escalating concerns over the financial crisis.

However, Tokyo players remained concerned about the course of the new international monetary policy being coordinated by the world's major central banks.

On currency markets at midday (0300 GMT), the dollar was quoted at 100.55-60 yen, up from Wednesday's 5 pm quote of 100.11-13 yen.

The euro was quoted at 1.3665-70 dollars, up from Wednesday's 5 pm quote of 1.3613-15 dollars, and at 137.43-48 yen, up from 136.28-32 yen. (dpa)