IRF4 is the gene responsible for gray hair, says study

Genetics have always been blamed for gray hair, but scientists have recently discovered the particular gene that turns hair gray. CBS News reported that a study released in the beginning of this month by Nature Communications has discovered that the IRF4 gene, which has been previously known to be culprit for light hair of Europeans, can be linked to gray hair as well.

Study researchers examined the DNA of 6,000 Latin American individuals, including the ones belonging to Mexico, Brazil, Colombia, Peru, and Chile, to find out the genes that decide hair color, density, and texture. With the help of the diverse gene pool, the researched found that the IRF4 gene is the culprit for gray hair.

Study author Kaustubh Adhikari from University College London said, “We already know several genes involved in balding and hair color, but this is the first time a gene for graying has been identified in humans, as well as other genes influencing hair shape and density”.

The gene plays a significant role in regulating and producing melanin, which provides hair its color, and decides the color of eyes and skin. Gray hair occurs in the case of less melanin production. The amount of melanin produced by the body is determined by genetics.

Adhikari said that when hair start turning gray, something happens that pushes this gene to produce even lesser amount of melanin. Adhikari added that now more specific functional questions can be asked.

Scientists are optimistic that the latest study will prove helpful in determining ways to postpone the graying process and could assist in better understanding of aging. They also have hopes that the particular gene will also be helpful in the forensic science and anthropology fields.