London, Apr 2 : Scientists have discovered a method that can manage the amount of fat that cells store for use as a back-up energy source, and can eventually lead to therapies for liver disease and diabetes.
Researchers at Albert Einstein College of Medicine of Yeshiva University have also found that the process, if disrupted, can enable cellular fat to accumulate, a key factor in age-related metabolic diseases such as obesity and type 2 diabetes.
They reckon that the discovery of this previously unknown fat-fighting pathway may lead to novel drugs for the treatment of metabolic syndrome - characterised by obesity, blood lipid disorders, and insulin resistance - and for a common liver disease known as "fatty liver" or steatohepatitis.