Washington, Apr 11 : Researchers from UT Southwestern Medical Centre have identified a molecule that prompts damaged heart cells to repair themselves after a heart attack.
The research team led by Drs. J. Michael DiMaio and Ildiko Bock-Marquette has discovered a molecule called, Thymosin beta-4 (TB4), which is expressed by embryos during the heart's development and encourages migration of heart cells.
They showed that introducing TB4 systemically after a heart attack encourages new growth and repair of heart cells as early as 24 hours after systemic injection.
In the mouse study, researchers found that TB4 initiates capillary tube formation of adult coronary endothelial cells in tissue culture.