Wearing only their undergarments, 1,600 participants covered a distance of 7-tenths of a mile down I Street Northwest, toward 18th Street. The participants covered the distance on foot in sub-freezing temperatures by walking, jogging and running. The run was part of the seventh annual Cupid’s Undie Run on February 13, 2016.

The distance is usually 1.5 miles, but it was reduced due to the extremely low temperatures. However, the dangerous temperatures could not discourage people from participating. The event involved running through Downtown Detroit for raising funds for the Children's Tumor Foundation. Though it was a usually hot winter, the temperatures dropped down significantly during past two days. But, half-naked participants ran to offer their support for fight against neurofibromatosis.

Neurofibromatosis is a genetic disorder related to nervous system. This disease adversely impacts the formation and development of nerve cells resulting in the formation of tumors along the nerves present throughout the body. Neurofibromatosis can result in pain, blindness, convulsions and learning disabilities.

According to the National Institute of Health, one person in every 3,000 to 4,000 across the world suffers from this disease. The event is organized to raise money for helping the Children's Tumor Foundation to fight against neurofibromatotis. "Everyone's here for a really good cause, and that can definitely warm your heart," said Jamie Sedlacek, the Race Director.

Donations of approximately $300,000 have been pledged, according to the organizers of the event. The first Cupid's Undie Run in Detroit witnessed approximately 500 runners and raised approximately $130,000.

In 2014, the number of participants increased to approximately 1,000, with donation amount reaching $200,000. In 2015, 1,200 people participated in the event and $280,000 was raised from the event. The participants first gathered at the House of Blues for warm up by consuming drinks and dancing. Participants lined-up at Euclid just before 2 pm.