AI and Machine Learning to Identify Fracture and Heart Disease Risk: Edith Cowan University Research
In a significant advancement for preventive healthcare, researchers from Australia and Canada have developed a sophisticated machine learning algorithm that can swiftly detect cardiovascular and fracture risk through routine bone density scans. By analyzing vertebral fracture assessment (VFA) images, the tool identifies abdominal aortic calcification (AAC)—a potent but often overlooked indicator of both heart disease and physical frailty. This innovation not only accelerates diagnostic timelines but also enables early detection in asymptomatic patients, especially older women. The integration of vascular insights into standard osteoporosis screenings could dramatically transform clinical approaches to fall and cardiovascular risk assessment in aging populations.
Revolutionary Algorithm Detects Cardiovascular Risk in Under a Minute
A new machine learning model developed collaboratively by Edith Cowan University (Australia) and University of Manitoba (Canada) has the capacity to identify critical health risks within seconds. Designed to process vertebral fracture assessment (VFA) images, this technology targets abdominal aortic calcification (AAC)—a well-established marker correlated with cardiac events such as heart attacks and strokes. Traditionally, analyzing these images required five to six minutes per scan by a trained expert. The novel algorithm now completes the task in less than one minute, making it a scalable solution for mass screening programs.
Abdominal Aortic Calcification: A Hidden Risk in Bone Scans
AAC is often present without symptoms, yet it plays a critical role in vascular pathology. The condition is characterized by calcium deposits in the abdominal aorta, which can signal increased arterial stiffness and systemic inflammation. According to ECU research fellow Cassandra Smith, nearly 58% of older women who underwent routine bone scans exhibited moderate to high levels of AAC, frequently without any awareness of the underlying cardiovascular threat. These findings underscore a diagnostic blind spot in traditional screenings, particularly for postmenopausal women, who are historically under-evaluated for cardiovascular disease.
Bridging the Gender Gap in Cardiac and Fall Risk Screening
"Women are chronically under-screened and under-treated for cardiovascular disease," noted Smith. The integration of this algorithm into existing osteoporosis screenings enables dual-purpose diagnostics—spotlighting both skeletal fragility and vascular compromise. The ability to detect AAC during a bone density scan allows for early intervention strategies, potentially altering the course of undiagnosed heart conditions in older female populations.
AAC as a Predictor of Falls and Fractures: A Paradigm Shift
In an extended analysis, Dr. Marc Sim, also from ECU, demonstrated that AAC is not merely a cardiovascular biomarker—it is also a significant predictor of fall and fracture risk. Surprisingly, AAC outperformed traditional risk indicators such as bone mineral density (BMD) and previous fall history. "The greater the arterial calcification, the higher the likelihood of debilitating falls and fractures," Sim emphasized. This revelation could revolutionize fall risk assessments, which typically neglect the role of vascular health in neuromuscular stability.
Clinical Implications: A New Era in Preventive Geriatric Care
The deployment of this algorithm can substantially enrich clinical insights derived from a routine bone scan. It empowers physicians to simultaneously evaluate skeletal and vascular risk, paving the way for multidimensional health interventions. Sim highlighted that this innovation offers actionable vascular data, which is currently absent from most fall-prevention frameworks. Incorporating AAC detection may prompt earlier pharmacologic and lifestyle interventions, tailored specifically to reduce fracture risk and cardiovascular mortality.
Conclusion: Integrating Artificial Intelligence into Preventive Medicine
The fusion of artificial intelligence with radiological diagnostics marks a watershed moment in geriatric medicine. By transforming bone density scans into dual-purpose diagnostic tools, this research underscores the importance of multi-system risk evaluation. With rising global concerns about aging populations, this machine learning breakthrough promises to reduce preventable hospitalizations, improve quality of life, and close critical gaps in women’s health screening. As healthcare systems pivot toward predictive and personalized medicine, innovations like this serve as powerful catalysts for change.