Washington, Feb 25 : A team of scientists, including an Indian-origin boffin, has identified a specific gene that plays a key role in the weight-gain response to a high-fat diet.
The study, conducted on mice, has suggested that blocking this gene could one day be a therapeutic strategy to reduce diet-related obesity and associated disorders, such as diabetes and liver damage, in humans.
The researchers found that a diet rich in fat induced production of this gene, called protein kinase C beta (PKC beta), in the fat cells of mice. These mice rapidly gained weight while eating a high-fat diet for 12 weeks.