Washington, March 15 : An Indian-origin researcher at Case Western Reserve University School of Medicine has found that imbalance of iron homeostasis is a common feature of prion disease-affected human, mouse, and hamster brains.
Dr. Neena Singh, who worked in collaboration with researchers from Creighton University, says that her team's findings provide new insight into the mechanism of neurotoxicity in prion disorders, and novel avenues for the development of therapeutic strategies.
Unlike other neurodegenerative conditions, prion disorders are sporadic, inherited, and infectious, and affect both humans and animals.
Mad cow disease in cattle, scrapie in sheep, and Creutzfeldt-Jakob disease in humans are some of its examples.