Washington, Oct 1 : Adolescents who feel relaxed when first exposed to nicotine from cigarettes are the ones likely to get hooked, a new study has revealed.

The University of Massachusetts Medical School conducted the study to find why some adolescents who try smoking get hooked to it while others do not.

“We know that nicotine can have an immediate impact on the brain, and yet we also know that not every adolescent who tries a cigarette gets hooked,” said the study’s lead author, Joseph R. DiFranza, MD, professor of family medicine & community health at UMMS.

“We wanted to know what accounts for the difference in vulnerability among adolescents who pick up that first cigarette,” he added.

Though personality factors often determine which young people will try smoking, it appears that it is the manner in which the brain reacts to nicotine, rather than personality, that plays a vital role in determining whether an adolescent will become hooked on nicotine once he or she has tried it.

“It appears that it is an addictive physiology and not an addictive personality that determines who will become dependent,” said Dr. DiFranza.

The four-year prospective study assessed 46 risk factors in categories such as personality, attitudes and beliefs about smoking, smoking by parents, siblings and peers, family and community involvement, and reactions to inhaling from a cigarette for the first time.

When all these factors were considered together, an experience of relaxation in response to the first dose of nicotine was the strongest predictor of future addiction. Other factors that predicted addiction were awareness of the cigarette advertising character Joe Camel, a novelty-seeking personality, and a depressed mood.

“These findings underscore our belief that the development of dependence is triggered by the changes in brain chemistry that follow the very first dose of nicotine,” said Dr DiFranza. (With inputs from ANI)