According to researchers from the University of California, San Francisco, they have found what is behind wasabi burn. The researchers have uncovered the structure of protein which is behind the burning sensation when an individual consume Japanese delicacy sushi with wasabi. As per the researchers, the new discovery could be helpful in improving future pain medications.

The protein, which is known as TRPA1, is able to detect the irritant in wasabi. TRPA1 starts a warning impulse. According to reports, the protein is also triggered by other irritants, including tear gas, and when a human body tissue is either injured or inflamed.

While providing information about the protein, David Julius, professor and physiology chair at the University of California, San Francisco, said in a university statement that the pain system is there to warn a human when the individual needs to avoid those things that can cause injury. It is there to enhance protective mechanisms, as per the professor. Julius is also co-author of the study.

From a long time, scientists were trying to figure out the structure of TRPA1 protein so that they can design more effective pain relief, but the imaging that they were determining was not sophisticated enough, as per reports. During the new study, the researchers used a new imaging technology, electron cryo-microscopy, and imaged the TRPA1 at a resolution of about 4 angstroms. A sheet of paper is approximately 1 million angstroms thick.

Julius further said, "Researchers are already experimenting with ways to block the response of the pain receptor. A few drugs have been developed that target TRPA1, and in our 3-D structure we can see where one such drug binds".

According to some reports, medicines that target the protein could also be effective in blocking out chronic itch linked with eczema and some nerve disorders.