New generation of broadly neutralizing antibodies could fight wide range of HIV strains
A team of scientists at Rockefeller University in New York has found an alternative treatment for HIV. According to the research team, the treatment could be a promising weapon in the battle against HIV infection. Their study published in the Journal Nature has revealed that mixture of extensively neutralizing antibodies could suppress the measure of HIV in blood.
This sort of HIV treatment uses clones of immune proteins taken from an uncommon person who has natural control of the sickness. Researchers believe that with further work, this could strengthen present medications.
Researchers recommend utilizing this treatment along with the current drugs or with different antibiotics.
In an HIV infected person, there is always a battle between the virus and the immune system. Although, the body produces new antibodies for the virus, the infection alters or mutates and manages to stay few steps ahead.
Scientists believe that an alternative treatment to anti-retroviral drugs can be offered by using synthetic antibodies that attach to the surface of proteins on the outer membrane of the virus. This would lead to new therapeutic vaccines one day.
HIV antibodies that were previously tested in humans gave disappointing results. However, antibodies tested at Rockefeller University are new generation of broadly neutralizing antibodies that could potentially fight a wide range of HIV strains.
Dr. Marina Caskey, co-first author of the study said, "One antibody alone, like one drug alone, will not be sufficient to suppress viral load for a long time because resistance will arise. What's special about these antibodies is that they have activity against over 80 per cent of HIV strains and they are extremely potent".
According to the researchers, the new antibody therapy was effective against 195 of 237 strains of the virus. Additionally, the study also raises hope for an HIV vaccine.