The first women to give birth following IVF treatment, Lesley Brown has died from septicemia after being admitted to hospital with gallstones at the age of 64 years.

Mrs Brown's name was recorded in medical history when she gave birth to her daughter, Louise. She was able to give birth to a baby girl after she failed to conceive for nine years. Her husband and Lesley heard about new research into In-Vitro Fertilisation and decided to go through it.

Lesley, from Whitchurch, Bristol agreed to experimental procedure and it worked eh first time. The same treatment was used later for Louise's sister Natalie. Since then more than three million babies have been born around the world through the treatment.

Lesley died at the Bristol Royal Infirmary on June 6 after a short illness. She has two daughters Louise and Natalie, a step daughter and five grandchildren. Her husband, John, passed away five years ago.

Daughter Louise said: "Mum was a very quiet and private person who ended up in the world spotlight because she wanted a family so much. We are all missing her terribly."