London: A senior cosmetic surgeon has warned that anti-wrinkle injection may cause irreversible damage to the facial tissues.

According to the French surgeon Dr Daniel Marchac, anti-wrinkle injections may seem a fast and perfect way to diminish the signs of ageing, but one in 20 of those gone for anti-wrinkle injections may end up with permanent damage to their subcutaneous tissue, the layer of fat underneath their skin and their fibrous connective tissue.

Dr. Marchac said, “All of the permanent fillers are creating, from time to time, serious problems with bumps and deformities, and sometimes you have to operate.”

“All serious plastic surgeons agree one should avoid permanent fillers. We will see in the future patients of 50 who have had 15 years of fillers, with fibrous, tough tissue we won't be able to do anything with,” he added.

“The serious things are the permanent fillers, and the second is abuse of resolvable fillers,” said Marchac.

Douglas McGeorge, President of British Association of Aesthetic Plastic, said, “The public needs to be realistic about the outcomes it can expect from new cosmetic treatments, at least until solid clinical evidence of their efficacy exists.”

His warning follows criticism faced by the British Ministers for inefficient regulation of the industry offering Botox and other filler treatments.

Dr. Marchac asked 900 surgeons for more evidence on anti-wrinkle injections like Botox, and now carbon dioxide.

The anti-wrinkle injections are of two types: one intended to be permanent and the other to be absorbed into the skin, and repeated after six months.

“I am really concerned that in 15 years we will see a lot of people with lumps and bumps and no good way to treat it,” said, Dr Sherrell Aston, chairman of plastic surgery at Manhattan Eye, Ear and Throat Hospital, New York.