Washington, Nov 12: Cambridge scientists have made a major breakthrough in rheumatoid arthritis. They have genetically engineered a drug-inducible form of Foxp3 gene, which when activated can prevent the autoimmune reaction characterised by the disease.
Rheumatoid arthritis is a painful, inflammatory type of arthritis that occurs when the body''s immune system attacks itself.
And the new strategy developed by scientists at the Medical Research Council''s Laboratory of Molecular Biology in Cambridge, may open the door for therapy development for rheumatoid arthritis.
Generally, immune cells develop to recognise foreign material – antigens; including bacteria - so that they can activate a response against them.