Alzheimer's Disease

Test to detect Alzheimer''s at its earliest stage ''seems possible'

 Test to detect Alzheimer''s at its earliest stage ''seems possible'London, Dec 22: UK researchers believe they can now detect the most common form of dementia - Alzheimer''s disease - at its earliest stage, many years before symptoms appear.

They reckon that a lumbar puncture test combined with a brain scan can identify patients with early tell-tale signs of dementia, reports the BBC.

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Why Alzheimer’s patients could forget that zebras have stripes

Why Alzheimer’s patients could forget that zebras have stripesWashington, Dec 21: A normal person wouldn't forget that a zebra has stripes or that a giraffe has four legs because these are concepts related to semantic memory - something that allows us to assign meaning to words and to recall general knowledge that we have learned.

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New molecular mechanisms involved in Alzheimer’s development identified

New molecular mechanisms involved in Alzheimer’s development identifiedWashington, Dec 17: Scientists have discovered new molecular mechanisms that may be involved in the development of Alzheimer's disease.

The study, a collaboration between bioinformaticians and cell biologists, was led by IRB Barcelona group leader and ICREA researcher Patrick Aloy.

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Super-early signs of Alzheimer''s revealed

Super-early signs of Alzheimer''s revealedWashington, Dec 17: A new study has revealed that people with a known, high risk for Alzheimer''s disease develop abnormal brain function even before the appearance of telltale amyloid plaques that are characteristic of the disease.

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High levels of ''good'' cholesterol linked to lower risk of Alzheimer''s

 High levels of ''good'' cholesterol linked to lower risk of Alzheimer''s Washington, Dec 14 : A new study has found that high levels of high-density lipoprotein (HDL) - also known as "good" cholesterol - appear to be associated with a reduced risk for Alzheimer''s disease in older adults.

Christiane Reitz and colleagues at Columbia University''s Taub Institute, New York, studied 1,130 older adults to examine the association of blood lipid (fat) levels with Alzheimer''s disease.

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New tool sweeps away Alzheimer's plaque from brain

New tool sweeps away Alzheimer's plaque from brainWashington, Dec 13 - A new molecular tool developed by US scientists has shown promise in 'clearing' the brain of plaque that triggers Alzheimer's disease.

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New method to cleanse brain of Alzheimer''s plaques developed

 New method to cleanse brain of Alzheimer''s plaques developed Washington, Dec 10 : University of Michigan scientists have developed new molecular tools that may help in "cleansing" the brain of amyloid plaques, implicated in Alzheimer''s disease.

A hallmark of Alzheimer''s disease-a neurodegenerative disease with no cure-is the aggregation of protein-like bits known as amyloid-beta peptides into clumps in the brain called plaques.

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Same gene linked to Alzheimer''s and heart attacks

Same gene linked to Alzheimer''s and heart attacksWashington, Dec 10: A new study has found that Alzheimer''s disease and heart attacks share common genetic basis.

It may pave way for the first genetic test on developing the risk of the diseases even at a young age.

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Eating blueberries, blackberries ''ward off Alzheimer''s, heart problems''

Eating blueberries, blackberries ''ward off Alzheimer''s, heart problems''London, Dec 8 : Consuming purple coloured fruit can keep age-related diseases such as Alzheimer''s, heart problems and cancer at bay, according to a new study.

The study, conducted by the University of Manchester, suggests that the odds of developing multiple sclerosis and Parkinson''s disease may also be reduced by consuming blueberries, blackberries, blackcurrants or plums.

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New mice study offers hope in the fight against Alzheimer''s

 New mice study offers hope in the fight against Alzheimer''s Washington, Dec 4 : In a new study, scientists found that dynamic regulation of the chaperone protein Hsp27 is required to get rid of abnormally accumulating tau in the brains of mice genetically modified to develop the memory-choking tau tangles associated with Alzheimer''s disease.

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Blood vessel dysfunction linked to heart disease also plays role in Alzheimer''s

 Blood vessel dysfunction linked to heart disease also plays role in Alzheimer''s Washington, Dec 3 : A new study has suggested that a dysfunction in the lining of blood vessels that is linked to cardiovascular illness also plays a role in the development of Alzheimer''s disease.

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Earliest brain changes linked to genetic risk of Alzheimer''s identified

Earliest brain changes linked to genetic risk of Alzheimer''s identifiedWashington, Dec 1 : Scientists have discovered the earliest brain changes associated with the genetic risk of developing Alzheimer''s disease.

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Chemicals in apple skins, red wine, tumeric could help fight Alzheimer''s

 Chemicals in apple skins, red wine, tumeric could help fight Alzheimer''s Washington, Nov 30 : A new study has revealed that supplements derived from apple skins, red wine and tumeric might someday help slow the onset and progression of Alzheimer''s and related diseases.

In scientists'' view, a group of chemicals called type-2 alkenes, which are widespread in both the environment and the brains of Alzheimer''s patients, act as major drivers of the disease.

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Walking slows Alzheimer's progress

AlzheimerLondon, Nov 29 : Walking five miles or about eight kilometres a week may slow the progression of Alzheimer's disease.

Walking slowed the decline in memory skills in people showing early signs of the disease and reduced brain shrinkage, symptomatic of Alzheimer's.

The team at University of Pittsburg in Pennsylvania, US, tracked for 10 years 299 healthy adults and 127 people with mild cognitive decline which can be a precursor to Alzheimer's disease, reports the Telegraph.

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New gene therapy may ‘fix memory problems in Alzheimer patients’

New gene therapy may ‘fix memory problems in Alzheimer patients’London, Nov 29 : Scientists at the Gladstone Institute of Neurological Disease (GIND) in San Francisco have discovered a new gene therapy that successfully fixed memory problems in mice with Alzheimer''s disease (AD).

Learning and memory requires communication between brain cells called neurons. This communication involves the release of chemicals from neurons that stimulate cell surface receptors on other neurons.

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Diabetes drug ‘may treat Alzheimer’s’

Diabetes drug ‘may treat Alzheimer’s’Washington, Nov 25 : A new study by scientists from Berlin, Bonn and Dundee has shown that the diabetes drug Metformin has an effect against one of the main causes of the Alzheimer's disease.

Metformin, a drug used in type 2-diabetes, might have the potential to also act against Alzheimer's disease. This has been shown in a study from scientists of the German Center for Neurodegenerative Diseases

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Cocktail of cheap drugs can prevent Alzheimer's?

Cocktail of cheap drugs can prevent Alzheimer's?London, Nov 23 - A low-cost diabetes drug taken with a red wine 'miracle pill' could prevent millions from suffering the agony of Alzheimer's, suggests new research.

The two-in-one cocktail could keep the brain healthy into old age, stopping dementia in some cases and halting it in others.

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Cocktail of cheap drugs ‘could prevent Alzheimer’s disease’

 Cocktail of cheap drugs ‘could prevent Alzheimer’s disease’ London, Nov 23 : A cheap diabetes drug taken with a red wine ‘miracle pill’ could prevent Alzheimer’s disease.

British doctors at Dundee University believe the two-in-one cocktail could keep the brain healthy into old age, stopping dementia developing in some cases and halting it in others.

The latest breakthrough centres on drugs called metformin and resveratrol, reports the Daily Mail.

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Instant test to detect Alzheimer's being developed

Instant test to detect Alzheimer's being developedLondon, Nov 12 - A 30-second test to spot the signs of Alzheimer's in those in their 40s is being developed by scientists.

The simple procedure, which warns of the debilitating disease decades before symptoms show, brings the hope of routine screening for dementia in as little as two years.

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Heavy smoking doubles Alzheimer's risk

Heavy smoking doubles Alzheimer's risk  London, Oct 27 : Middle-aged smokers who puff 40 cigarettes a day more than double their risk of developing Alzheimer's disease, a study shows.

The study also found that heavy smoking greatly increased chances of another common form of dementia.

Scientists in the US followed the progress of more than 21,000 middle-aged men and women for an average of 23 years.

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Critical ''traffic engineer'' of the nervous system found

AlzheimerLondon, Sep 9 : Researchers have identified a critical enzyme that keeps traffic flowing in the right direction in the nervous system—a feat that could pave the way for new treatments for conditions such as Alzheimer''s and Parkinson''s disease.

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Alzheimer''s disease caused by brain ‘rust’, says Oz scientist

AlzheimerMelbourne, Sep 06 : Australian scientists have revealed that accumulation of brain "rust" is a cause of Alzheimer''s disease.

An imbalance in the metals needed for healthy brain function has been found at the root of the degenerative disease, which afflicts 10 per cent of people, aged over 60.

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New mechanism to pave way for methods to screen Alzheimer''s drugs

New mechanism to pave way for methods to screen Alzheimer''s drugsWashington, Aug 21 : Researchers at UC Davis have found a mechanism by which the amyloid protein damages the brain— a finding that could lead to new ways to screen drugs for Alzheimer''s and similar diseases.

The researchers found that brain cells exposed to a form of the amyloid beta protein, the molecule linked to Alzheimer''s disease, become stiffer and bend less under pressure.

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Why Alzheimer''s drug is both safe and effective

Why Alzheimer''s drug is both safe and effectiveWashington, Aug 19 : A new study has unravelled exactly how memantine-a drug used to treat Alzheimer''s disease- helps patients without causing serious side effects.

It is known that memantine (marketed in the United States as Namenda), which is currently FDA-approved can treat moderate-to-severe Alzheimer''s disease.

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Mid-life stress ups Alzheimer's risk for women

Mid-life stress ups Alzheimer's risk for womenLondon, Aug 17 - Women, who experience repeated stress and anxiety in mid-life, can face up to twice the risk of developing dementia than their normal peers.

Swedish researchers followed the progress of 1,415 women, with three surveys in 1968, 1974 and 1980 to assess the levels of psychological stress. The women were aged between 38 and 60 at the beginning of the study, says a Daily Mail report.

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