Body fat, the main reason behind for worsening killer diseases such as cardio-related diseases, diabetes and even cancer has been suggested as a risk factor even for a person who is lean, with no fat depositions.

It is believed that a gene called PAI-1, roused like a terrifying sleeper cell, in this case by fatty tissue or the free-roaming fat molecules that originates from the oily foods, hinders the medicine which results in aggravating the killer cells.

An endocrinologist at New York's Albert Einstein College of Medicine Mr. Kishore explains that, "Understanding these mechanisms and identifying the fat-derived factors that activate marcro-phages (mutinous defensive cells) could lead to new targeted therapies for these conditions, which have increased to epidemic proportions globally but particularly in India."

Kishore and his colleagues while performing an experiment injected healthy, non-diabetic adults with fats typically seen in obese people and those with diabetes. The results showed that the healthy bodies stopped reacting effectively to insulin, the main compound against diabetes; and a rise in levels of PAI-1. To this Kishore added, "We found that elevated levels of fat molecules circulating in blood, as seen in obesity and Type 2 diabetes, can directly increase PAI-1 gene expression in fat."